Shares of Mast Therapeutics Inc. MSTX are up .11 to .85 today. MSTX is in the middle of the 52 week range.

Today paper traded 250 MSTX Jul 1 calls for .15 PBF Sep 30 calls for 1.80.? The ADV is 546 contracts.? The OI is 96 contracts.

The volume went up in one block.? The bigger volume has followed with call briskly trading over 5000 contracts mostly around the .15 level.? Could be closing and opening paper on huge open interest, but it?s definitely a high risk sale. Much of the trade is scattered buying.? It is worth checking the OI to see if this is a buildup of buying paper.

30-day implied volatility is 129%.? ?10-day implied volatility is 33%.? 30-day implied volatility is trading above the 10-day historical volatility.

Mast Therapeutics, Inc., formerly ADVENTRX Pharmaceuticals, Inc., is a development-stage company biopharmaceutical company focused on developing product candidates.?